Comparison of the Bronchodilator Effects of Aerosol Fenoterol and lsoproterenol*
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چکیده
Aerosolized fenoterol in a dosage of 400 g was compared to Isoproterenol 150 g in 31 asthmatic subjects during the course of a double-blind parallel 90-day study. Bronchodilator activities of the two drugs were evaluated for up to 6 hours on days 1, 45 and 90. Analysis of the data revealed that fenoterol consistently produced a significantly greater increase in FEy1, FEF25-75% and Gaw/YL. Specific airway conductance Increased on each test day 25 percent or more above baseline for over three hours after use of fenoterol and for only one hour after use of IsoproterenoL Fenoterol had less effect upon the
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تاریخ انتشار 2005